Progesterone is a hormone produced in the ovaries, adrenal glands, and placenta (during pregnancy) in individuals with female reproductive systems, as well as in smaller amounts in individuals with male reproductive systems. It is known as the “pregnancy hormone” because of its crucial role in the menstrual cycle and pregnancy.

Because progesterone levels rise after ovulation, a progesterone blood test can confirm if ovulation has occurred. During pregnancy, adequate levels of progesterone produced by the placenta are essential to the maintenance of the uterine lining, prevention of uterine contractions, and suppression of the immune system (to prevent it from rejecting the developing fetus).

Who should take this test?

This test is often used to assess fertility and confirm ovulation in individuals who are trying to conceive, as well as to monitor early pregnancy and evaluate the risk of miscarriage in those who are pregnant. It can also aid in the diagnosis of menstrual disorders like amenorrhea and polycystic ovary syndrome (PCOS). Transgender individuals who are undergoing hormone replacement therapy (HRT) may have progesterone levels checked as part of their overall hormone profile assessment.

What is included in this test?

This blood test measures:

• Progesterone

This test uses equilibrium ultrafiltration to separate the free testosterone from the bound testosterone in the blood sample.

How will taking this test benefit me?

A progesterone test provides valuable information about an individual's reproductive health and hormonal balance. Knowing whether ovulation has occurred is essential for individuals trying to conceive. For those who are pregnant, progesterone testing can help guide decisions and interventions to ensure a healthy pregnancy.

For people struggling with menstrual disorders, progesterone testing can help healthcare providers identify underlying causes and develop targeted treatment plans.

For transgender individuals undergoing hormone replacement therapy, progesterone testing helps ensure hormone levels are within desired ranges.